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Notably, it significantly lowered indicators of arterial and coronary health risks compared to traditional hypolipidemic drugs. The results suggest that incorporating fermented soymilk may offer a natural way to support heart health and alleviate hyperlipidemia.
After this period, we observed notable improvements in various cardiovascular parameters, including blood pressure and key atherogenic indices. This suggests that probiotics might help lower the risk of future cardiovascular disease in those living with diabetes.
However, we recognize that more research is necessary to fully understand these benefits.
In experiments with mice, we saw a decrease in harmful lipoprotein buildup in arteries, suggesting potential anti-atherosclerotic effects. While these results are promising, further studies are necessary to fully understand how L. acidophilus K301 could be used in cardiovascular disease prevention.
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Notably, it significantly lowered indicators of arterial and coronary health risks compared to traditional hypolipidemic drugs. The results suggest that incorporating fermented soymilk may offer a natural way to support heart health and alleviate hyperlipidemia.
The results showed that this probiotic-rich food helped normalize heart electrical activity and reduced heart enlargement markers compared to the doxorubicin-only group. It also lowered harmful inflammatory markers and improved beneficial antioxidant levels.
However, while these findings are promising, they are based on animal models and may not directly translate to humans.
Our primary focus was on whether these probiotics could reduce in-hospital mortality and the occurrence of significant cardiovascular events. While the results are still pending, our findings could provide insights into the use of probiotics as a supportive treatment in heart care.
Our observations indicated improvements in several blood parameters, suggesting a positive influence on heart health. Although we found benefits, more research is essential to fully understand probiotics' role in supporting heart function.
After this period, we observed notable improvements in various cardiovascular parameters, including blood pressure and key atherogenic indices. This suggests that probiotics might help lower the risk of future cardiovascular disease in those living with diabetes.
However, we recognize that more research is necessary to fully understand these benefits.
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Frequently Asked Questions
Cardiovascular disease (CVD) is a broad term that encompasses a range of heart and blood vessel disorders. This can include conditions such as coronary artery disease, which leads to heart attacks; cerebrovascular disease that results in strokes; and peripheral artery disease affecting blood flow to the limbs. The key risk factors for CVD often include high blood pressure, high cholesterol, obesity, smoking, a sedentary lifestyle, and diabetes. By identifying and managing these risk factors, individuals can significantly reduce their likelihood of developing cardiovascular problems.
Prevention and treatment strategies often involve lifestyle modifications such as adopting a heart-healthy diet rich in fruits, vegetables, whole grains, and lean proteins, alongside engaging in regular physical activity. In some cases, medications might be necessary to control blood pressure or cholesterol levels. Regular check-ups with a healthcare provider are essential for monitoring heart health, especially for individuals with a family history of CVD. Understanding the signs and symptoms of cardiovascular issues—like chest pain, shortness of breath, or fatigue—can help in seeking timely medical attention, ultimately leading to better outcomes.
Acidophilus, scientifically known as Lactobacillus acidophilus, is a type of beneficial bacteria that is commonly found in the human gut, as well as in fermented foods like yogurt and dietary supplements. This probiotic strain plays a crucial role in maintaining gut health by aiding digestion, enhancing nutrient absorption, and supporting the immune system. It is particularly known for its ability to break down lactose, making it easier for lactose-intolerant individuals to digest dairy products.
In addition to its digestive benefits, acidophilus has been studied for its potential to prevent or alleviate certain gastrointestinal issues, such as diarrhea and irritable bowel syndrome (IBS). Some research also suggests that it may support vaginal health by helping to maintain a balanced microbiome in women. When selecting a probiotic supplement that contains acidophilus, it is essential to look for products that contain live and active cultures, ensuring that you receive the full benefits of this beneficial bacteria. Always consult with a healthcare professional before beginning any new supplement regimen.
Based on user reviews, the timeframe in which individuals report noticeable results from taking this supplement varies widely. Some users suggest improvements in digestive health and overall wellbeing within just a week of consistent use. For instance, one reviewer noted a discernible enhancement in their skin condition after seven days of taking the probiotic blend (Read Review). Other users, particularly those dealing with more chronic conditions, indicated that significant benefits, especially in terms of regularity or symptom relief, can take several months, with one mentioning a complete resolution of their chronic IBS symptoms within six months of combined treatments (Read Review).
Overall, while some individuals may experience quick results, particularly for gut health, others may need to commit to a longer course before they see substantive changes. It’s essential to maintain consistent usage as noted by users who reported ongoing benefits when taken regularly (Read Review). If you're considering this supplement for cardiovascular health specifically, results may also depend on individual health circumstances and how your body responds to the probiotics.
The question of whether probiotics are backed by scientific research in the context of cardiovascular disease is somewhat nuanced. Several studies have indicated potential benefits of probiotics on heart health. For example, research has shown that specific probiotic strains, like Lactobacillus acidophilus, may lead to notable improvements in cardiovascular parameters such as cholesterol levels and inflammation markers, suggesting they might help reduce the risk of future cardiovascular issues ([1]). Additionally, in the context of type-2 diabetes, studies revealed that probiotics could improve cardiovascular indices in patients, reinforcing their potential role in heart health management ([5]).
However, not all findings are uniformly positive. Some studies, like the one focusing on non-alcoholic steatohepatitis (NASH) patients, showed no significant cardiovascular risk reduction from probiotic supplementation ([3]). Furthermore, while animal studies indicated that probiotics might help prevent heart damage and reduce inflammation ([10]), more research is essential to ascertain their effects in humans. Overall, while there is promising data suggesting that probiotics could support cardiovascular health, ongoing studies are necessary to fully understand their effectiveness and practical application in preventing cardiovascular disease.
Based on user reviews, many individuals report various improvements in digestive health and symptom relief after using the Lactobacillus acidophilus probiotic blend. Several users with chronic conditions, such as IBS and gastrointestinal discomfort, have noted significant benefits. For instance, one user with chronic IBS reported a complete symptom resolution after six months of consistent use alongside other treatments (Read Review). Another user claimed that the product has greatly alleviated their boyfriend's Crohn's disease symptoms, highlighting substantial relief from gastrointestinal issues and reduced gas (Read Review).
In addition to digestive relief, some users have observed improvements in oral health and immune function. One individual shared that applying the product directly to swollen gums led to a significant reduction in swelling within an hour, indicating its potential benefits for periodontal health (Read Review). Another user mentioned feeling an overall boost in immunity, highlighting the broader health benefits this probiotic may offer (Read Review). While these anecdotal experiences are promising, it's vital to remember that individual results can vary significantly.
Users have reported mixed experiences when combining Lactobacillus acidophilus with other supplements while managing cardiovascular disease. One user emphasized the importance of pairing this probiotic with biotin to improve oral health, particularly in combating periodontal disease after experiencing swollen gums (Read Review). Additionally, another reviewer indicated that their father, who suffers from both diabetes and cardiovascular disease, found it effective for alleviating constipation, suggesting that the probiotic may have tangible benefits even within such complex health conditions (Read Review).
While these anecdotes suggest potential benefits of combining this supplement with others, users have also noted varying results based on individual health circumstances. For instance, one user mentioned their boyfriend with Crohn's disease experienced considerable relief from gastrointestinal symptoms when using the product (Read Review). Overall, while there are positive reports regarding the combination of Lactobacillus acidophilus with other treatments, it appears that individual results can differ significantly, highlighting the need for personal experimentation and cautious monitoring when integrating multiple supplements for cardiovascular health.
After this period, we observed notable improvements in various cardiovascular parameters, including blood pressure and key atherogenic indices. This suggests that probiotics might help lower the risk of future cardiovascular disease in those living with diabetes.
However, we recognize that more research is necessary to fully understand these benefits.
After the treatment, we observed no significant reduction in cardiovascular risk markers between the two groups. This indicates that, in this context, probiotics may not be effective for lowering cardiovascular risks in NASH patients.
We observed that probiotics reduced harmful toxins and improved heart function. They showed potential in protecting against heart issues by lowering inflammation markers and oxidative stress damage. This suggests probiotics might be a valuable preventive option for those at risk for heart disease in the future.
References
- Chen Y, Chen R, Wang X, Zhou Y, Hong L, et al. Effect of probiotic supplementation on in-hospital mortality in patients with acute myocardial infarction: a study protocol for an open-label, randomized, controlled, superiority clinical trial. Trials. 2023;24:429. doi:10.1186/s13063-023-07443-5
- Borshchev YY, Sonin DL, Burovenko IY, Borshchev VY, Cheburkin YV, et al. The Effect of Probiotic Strains on Myocardial Infarction Size, Biochemical and Immunological Parameters in Rats with Systemic Inflammatory Response Syndrome and Polymorbidity. J Evol Biochem Physiol. 2022;58:2058. doi:10.1134/S0022093022060321
- Barcelos STA, Silva-Sperb AS, Moraes HA, Longo L, de Moura BC, et al. Oral 24-week probiotics supplementation did not decrease cardiovascular risk markers in patients with biopsy proven NASH: A double-blind placebo-controlled randomized study. Ann Hepatol. 2023;28:100769. doi:10.1016/j.aohep.2022.100769
- Nabhani Z, Clark CCT, Goudarzi N, Hariri Far A, Razmpoosh E. The effect of synbiotic supplementation on atherogenic indices, hs-CRP, and malondialdehyde, as major CVD-related parameters, in women with gestational diabetes mellitus: a secondary data-analysis of a randomized double-blind, placebo-controlled study. Diabetol Metab Syndr. 2022;14:87. doi:10.1186/s13098-022-00858-1
- Ahmadian F, Razmpoosh E, Ejtahed HS, Javadi M, Mirmiran P, et al. Effects of probiotic supplementation on major cardiovascular-related parameters in patients with type-2 diabetes mellitus: a secondary-data analysis of a randomized double-blind controlled trial. Diabetol Metab Syndr. 2022;14:52. doi:10.1186/s13098-022-00822-z
- Romão da Silva LF, de Oliveira Y, de Souza EL, de Luna Freire MO, Braga VA, et al. Effects of probiotic therapy on cardio-metabolic parameters and autonomic modulation in hypertensive women: a randomized, triple-blind, placebo-controlled trial. Food Funct. 2020;11:7152. doi:10.1039/d0fo01661f
- Haghighat N, Mohammadshahi M, Shayanpour S, Haghighizadeh MH. Effect of Synbiotic and Probiotic Supplementation on Serum Levels of Endothelial Cell Adhesion Molecules in Hemodialysis Patients: a Randomized Control Study. Probiotics Antimicrob Proteins. 2019;11:1210. doi:10.1007/s12602-018-9477-9
- Chen J, Wu Y, Yang C, Xu X, Meng Y. Antioxidant and hypolipidemic effects of soymilk fermented via Lactococcus acidophilus MF204. Food Funct. 2017;8:4414. doi:10.1039/c7fo00701a
- Farrokhian A, Raygan F, Soltani A, Tajabadi-Ebrahimi M, Sharifi Esfahani M, et al. The Effects of Synbiotic Supplementation on Carotid Intima-Media Thickness, Biomarkers of Inflammation, and Oxidative Stress in People with Overweight, Diabetes, and Coronary Heart Disease: a Randomized, Double-Blind, Placebo-Controlled Trial. Probiotics Antimicrob Proteins. 2019;11:133. doi:10.1007/s12602-017-9343-1
- Sadeghzadeh J, Vakili A, Sameni HR, Shadnoush M, Bandegi AR, et al. The Effect of Oral Consumption of Probiotics in Prevention of Heart Injury in a Rat Myocardial Infarction Model: a Histopathological, Hemodynamic and Biochemical Evaluation. Iran Biomed J. 2017;21:174.
- Tajabadi-Ebrahimi M, Sharifi N, Farrokhian A, Raygan F, Karamali F, et al. A Randomized Controlled Clinical Trial Investigating the Effect of Synbiotic Administration on Markers of Insulin Metabolism and Lipid Profiles in Overweight Type 2 Diabetic Patients with Coronary Heart Disease. Exp Clin Endocrinol Diabetes. 2017;125:21. doi:10.1055/s-0042-105441
- Hong YF, Kim H, Kim HS, Park WJ, Kim JY, et al. Lactobacillus acidophilus K301 Inhibits Atherogenesis via Induction of 24 (S), 25-Epoxycholesterol-Mediated ABCA1 and ABCG1 Production and Cholesterol Efflux in Macrophages. PLoS One. 2016;11:e0154302. doi:10.1371/journal.pone.0154302
- Kalani M, Hodjati H, Sajedi Khanian M, Doroudchi M. Lactobacillus acidophilus Increases the Anti-apoptotic Micro RNA-21 and Decreases the Pro-inflammatory Micro RNA-155 in the LPS-Treated Human Endothelial Cells. Probiotics Antimicrob Proteins. 2016;8:61. doi:10.1007/s12602-016-9214-1
- Sun J, Buys N. Effects of probiotics consumption on lowering lipids and CVD risk factors: a systematic review and meta-analysis of randomized controlled trials. Ann Med. 2015;47:430. doi:10.3109/07853890.2015.1071872
- Abu-Elsaad NM, Abd Elhameed AG, El-Karef A, Ibrahim TM. Yogurt Containing the Probacteria Lactobacillus acidophilus Combined with Natural Antioxidants Mitigates Doxorubicin-Induced Cardiomyopathy in Rats. J Med Food. 2015;18:950. doi:10.1089/jmf.2014.0104
- Tomaro-Duchesneau C, Jones ML, Shah D, Jain P, Saha S, et al. Cholesterol assimilation by Lactobacillus probiotic bacteria: an in vitro investigation. Biomed Res Int. 2014;2014:380316. doi:10.1155/2014/380316
